Improved APL survival in developing countries

December 7th, 2009 at 1:45 pm (Uncategorized)

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Here is an interesting article on improved APL survival stats in developing=
countries,

http://www.hemonctoday.com/article.aspx?rid=3D51173

Its good to see treatments such as Arsenic and Retinoic Acid having a world=
wide impact on APL.

Chris

[cid:bayside.jpg]
Bayside Networks
Information Technology Service and Support

http://baysidenetworks.com

3655 Nobel Drive Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4080 Toll-free

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Here is an interesting article on improved APL surviva=
l
stats in developing countries,

 

http://www.hemonctoday.com/article.aspx?rid=3D51173

 

Its good to see treatments such as Arsenic and Retinoi=
c Acid
having a worldwide impact on APL.

 

Chris












Bayside Networks

Information Technology Ser=
vice and Support
http://baysidenetworks.com
3655 Nobel Drive =
Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4=
080 Toll-free


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4 Comments

Prominent College Offensive Coordinator Coach diagnosed with APL

November 25th, 2009 at 8:49 am (Uncategorized)

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I wish Dana Bible the best for his treatment.

According to this article he is going in for 30 days of initial treatment f=
or APL:

http://www.sportingnews.com/college-football/article/2009-11-24/north-carol=

ina-nc-state-preview

[cid:bayside.jpg]
Bayside Networks
Information Technology Service and Support

http://baysidenetworks.com

3655 Nobel Drive Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4080 Toll-free

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I wish Dana Bible the best for his treatment. &nb=
sp;

 

According to this article he is going in for 30 days o=
f initial
treatment for APL:

 

http://www.sportingnews.com/college-football/=
article/2009-11-24/north-carolina-nc-state-preview

 

 

 












Bayside Networks

Information Technology Ser=
vice and Support
http://baysidenetworks.com
3655 Nobel Drive =
Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4=
080 Toll-free


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1 Comments

Brief mention of a young APL survivor

November 11th, 2009 at 9:09 am (Uncategorized)

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APL isn’t mentioned in the news very often – it’s a rare disease so that’s =
understandable. Here’s an article that briefly mentions a girl named Ashe=
ly Jones that was diagnosed and treated at 9 year’s old and is doing fine n=
ow at 14,

http://www.explorernews.com/articles/2009/11/11/news/doc4af9f3fbe35e8187370=

243.txt

[cid:bayside.jpg]
Bayside Networks
Information Technology Service and Support

http://baysidenetworks.com

3655 Nobel Drive Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4080 Toll-free

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APL isn’t mentioned in the news very often &#821=
1; it’s
a rare disease so that’s understandable.   Here’s an =
article that
briefly mentions a girl named Ashely Jones that was diagnosed and treated a=
t 9
year’s old and is doing fine now at 14,

 

http://www.explorernews.com/articles/2009/11/11/news/doc4a=
f9f3fbe35e8187370243.txt

 

 












Bayside Networks

Information Technology Ser=
vice and Support
http://baysidenetworks.com
3655 Nobel Drive =
Suite 640
San Diego CA 92122-1052

858-654-4080 Phone
877-654-4=
080 Toll-free


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1 Comments

News article about an APL survivor, Vesanoid is mentioned, Side Effects?

October 12th, 2009 at 9:38 am (Uncategorized)

I’m always watching for first hand =
information from
people that have been treated for APL.     Such =
stories don’t
appear very often.  

 

This article describes a 41 yr old male named Rick =
that
experienced a lot of complications apparently from Vesanoid.   =
Seems
like any drug that is active against APL blasts can cause tremendous =
potential
problems like this.     Rick may have suffered from =
“retinoic
acid syndrome” as the blasts were being cleared.   =
Arsenic can
also cause similar side effects.

 

I’m not sure its always fair to report =
problems like
this as “Vesanoid specific” (the article doesn’t use =
is term
but the cause and effect is implied).

 

My concern is that people might read an article =
like this
and assume Vesanoid is a “bad drug.”   Well, a lot =
of
drugs including Vesanoid have potentially terrible side =
effects.  
The problem is that untreated, or poorly treated leukemia is usually =
worse than
any drug!  

 

Anita experienced some troubles while she was =
taking
Vesanoid but nothing severe like this article mentions.

 

Its nice to see that Rick is doing =
well.   I
wonder if he will also receive any Arsenic treatment?    =
Some
treatment centers are offering both Vesanoid and Arsenic for their front =
line APL
treatment regimen now.

 

h=
ttp://www.knoxnews.com/news/2009/oct/12/returning-the-favors/

 

 

Chris

 

Comments

Amazing story, leukemia and heart transplant survivor, Ironman participant

October 9th, 2009 at 8:38 am (Uncategorized)

 

The next time I feel lazy or unmotivated – I =
will try
to think of this interesting guy,

 

Com=
petitor
takes on Ironman after heart transplant

 

Chris

 

1 Comments

The use of the word “cure” in connection with leukemia

October 7th, 2009 at 8:12 pm (Uncategorized)

CML is one of the few leukemias that you sometime =
hear the
word “cure” in connection with.   You also hear =
the “c”
word occasionally in connection with some of the treatment regimens for =
APL.

 

Anita has a friend that has been treated =
successfully (so
far) with Glivec so I was interested to hear this story,

 

http://www.upi.com/Top_News/2009/10/0=
7/Leukemia-drug-Australia-trials-promising/UPI-80311254947768/

 

Chris

 

1 Comments

An improved ability to detect residual leukemia, magnetic nanoparticles

October 7th, 2009 at 8:03 pm (Uncategorized)

I thought this article was interesting.  It =
discusses a
new leukemia diagnostic / detection technique that should help improve =
the
ability to detect extremely small residual amounts of leukemic =
cells.

 

I would imagine that this method might be used to =
gather a marrow
or blood sample that would then be used with a  sensitive PCR test =
for
residual leukemia.

 

http://www.modernmedicine.com/modernmedici=
ne/Pathology/Technique-May-Aid-Detection-of-Residual-Leukemia/ArticleNews=
Feed/Article/detail/632256?contextCategoryId=3D40165

 

PCR tests are sensitive to begin with and this =
technique
might be able to help make them even more sensitive.  My question =
is what should
be done with an even more sensitive detection method for leukemia =
cells?  

 

Anita’s Dr’s always seemed a bit unsure =
what to
do if a positive PCR test was to come through for her.   The =
best
answer I could ever get was that “all the Dr’s oncologists =
in our
group would talk” if a positive result came through and they would =
decide
“what do to next” together.    =

 

I actually liked the “all the Dr’s will =
talk
about what to do next” – that sounded =
reasonable.   
I think that answer is code for “We don’t know what to do if =
that
happens” but we’ll do our best to make a good =
decision.

 

My thought is that a further improvement of PCR =
sensitivity
could offer an even earlier warning of possible relapse and the need for =
more
frequent testing upon which a decision for further treatment could be =
based if
relapse became more apparent.

 

I’ll leave it up to you to find, but there is =
an
earlier article on this blog that discusses the fact that a few stray =
(apparent)
leukemia cells don’t always mean a relapse is certain.  =

 

In fact, cells that exhibit genetic markers (such =
as CD33) that
are consistent with leukemia cells are sometimes found in healthy people =
that
will never develop leukemia!   Points like this help me =
understand
why Anita’s Dr’s were loathe to explain how or what =
treatment
decision would result if a positive PCR test was to come =
in.

 

Anita is still doing fine, in her second here of =
nursing
school now.

 

Chris

 

 

1 Comments